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Fluorescence enhancement of bis-acridine orange peptide, BAO, upon binding to double stranded DNA

Keiji Mizuki1, Yutaka Sakakibara, Hiroyuki Ueyama

  • 1Department of Applied Chemistry, Faculty of Engineering, Kyushu University, Fukuoka, 812-8581, Japan.

Organic & Biomolecular Chemistry
|February 11, 2005
PubMed

Abstract:

Bis-acridine orange peptides carrying two acridine oranges at the epsilon-amino moieties of both terminal lysines of a tetra(lysine) chain showed a ca. 200-fold fluorescence enhancement upon addition of double stranded DNA.

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