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Depression in patients with heart failure
Cheryl Westlake1, Kathleen Dracup, Gregg Fonarow
1California State University, Fullerton, California, USA.
Insights
Depression is common in heart failure patients. Interventions targeting perceived control and neuroticism may help reduce depression in this population.
Area of Science:
- Cardiology
- Psychiatry
- Psychology
Background:
- Psychological comorbidities, especially depression, frequently complicate heart failure management.
- Understanding the prevalence and correlates of depression in heart failure patients is crucial for effective clinical care.
Purpose of the Study:
- To determine the prevalence of depression among heart failure patients.
- To identify differences between patients with minimal versus mild to severe depression.
- To explore the factors associated with depression in this patient group.
Main Methods:
- A cohort of 200 heart failure patients with systolic dysfunction was assessed.
- Psychological evaluations included assessments of depression, perceived control, neuroticism, educational needs, and social support.
- Clinical data included New York Heart Association (NYHA) class, ejection fraction, maximal oxygen uptake, and 6-minute walk distance.
Main Results:
- Over half of the patients (52.5%) reported minimal depression; 47.5% reported mild to severe depression.
- Significant differences between minimal and mild-to-severe depression groups included NYHA class, maximal oxygen uptake, 6-minute walk distance, beta-blocker use, perceived control, and neuroticism.
- Physical and psychosocial variables explained 48.6% of the variance in depression among patients experiencing it.
Conclusions:
- While over half of the studied heart failure patients did not report significant depression, a substantial portion did.
- Physical and psychosocial factors are significantly associated with depression in heart failure.
- Interventions focused on enhancing perceived control, reducing neuroticism, and addressing educational needs may be beneficial for reducing depression in heart failure patients.
Background:
Psychologic comorbidities, particularly depression, often accompany heart failure and add to the complexity of clinical management. We conducted a study to describe the prevalence of depression, the differences between patients with minimal versus mild to severe depression, and the correlates of depression in patients with heart failure.
Methods And Results:
Data were collected from 200 patients with symptoms of heart failure resulting from systolic dysfunction. Psychologic assessment included depression, perceived control, neuroticism, educational needs, and social support/network. Patients were, on average, 57.0 (+/-12.1) years old, male (168, 84.0%), and in New York Heart Association (NYHA) class II or III (n=140, 70.0%) with a mean ejection fraction of 25.5+/-6.4%. They had an average maximal oxygen uptake of 15.8 (+/-4.6) mL x kg x min and 6-minute walk distance of 1345.0 (+/-302.1) feet. Minimal depression was described by 105 (52.5%) patients, mild by 62 (31%), moderate by 30 (15%), and severe by 3 (1.5%). The significant differences between patients with minimal depression compared to mild to severe depression were NYHA class (chi2=14.05, P=.003), maximal oxygen uptake (t=2.62, P=.010), 6-minute walk distance (t=4.22, P < .001), beta-blocker therapy (chi2=15.21, P < .001), perceived control (t=7.93, P < .001), and neuroticism (t=-8.85, P < .001).
Conclusions:
More than half the patients studied did not report experiencing significant depression. In those who did, both physical and psychosocial variables accounted for 48.6% of the variance. These findings warrant further research and indicate a need to test interventions aimed at enhancing perceived control, reducing neuroticism, and meeting educational needs to reduce depression in patients with heart failure.
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