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Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
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Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure

Published on: June 10, 2025

Significance of predischarge BNP on one-year outcome in decompensated heart failure--comparative study with

Yoko Hamada1, Nobuaki Tanaka, Kazuya Murata

  • 1Division of Cardiovascular Medicine, Department of Medical Bioregulation, Yamaguchi University School of Medicine, Yamaguchi, Japan.

Journal of Cardiac Failure
|February 11, 2005
PubMed

Insights

Predischarge B-type natriuretic peptide (BNP) levels, not admission levels, predict rehospitalization for congestive heart failure (CHF) within a year. Etiology did not impact BNP or echo-Doppler index prognosis.

Area of Science:

  • Cardiology
  • Biomarkers
  • Heart Failure Management

Background:

  • Congestive heart failure (CHF) prognosis relies on cardiac natriuretic peptides and echo-Doppler indexes.
  • Etiology-specific prognostic differences in CHF require further investigation.
  • Assessing transmitral flow (TMF) and B-type natriuretic peptide (BNP) in ischemic vs. nonischemic CHF.

Purpose of the Study:

  • Evaluate the prognostic value of TMF and BNP in acutely decompensated CHF.
  • Compare prognostic indicators in ischemic (old myocardial infarction - OMI) and nonischemic (idiopathic dilated cardiomyopathy - DCM) etiologies.
  • Determine if admission or predischarge measurements are more predictive of rehospitalization.

Main Methods:

  • Studied 52 chronic CHF patients (31 OMI, 21 DCM) during acute decompensation.
  • Performed echo-Doppler studies and measured plasma BNP on admission and predischarge.
  • Monitored rehospitalization rates over 1 year, comparing patients with stable courses (S group) to those rehospitalized (R group).

Main Results:

  • Admission TMF and BNP levels were similar between DCM and OMI groups, and between R and S groups.
  • Predischarge BNP levels were significantly higher in the rehospitalized (R) group compared to the stable (S) group.
  • Kaplan-Meier analysis confirmed predischarge BNP's influence on 1-year prognosis.

Conclusions:

  • Predischarge BNP levels, rather than admission levels, are predictive of 1-year rehospitalization risk in CHF.
  • No significant differences were observed between BNP and echo-Doppler indexes concerning CHF etiology (OMI vs. DCM).
Abstract

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