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Related Experiment Videos

Validation of the urgency perception scale.

Linda Cardozo1, Karin S Coyne, Eboo Versi

  • 1Urogynaecology, Kings College Hospital, London, UK. coyne@medtap.com

BJU International
|February 12, 2005
PubMed
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The Urgency Perception Scale (UPS) effectively measures urinary urgency in overactive bladder (OAB) patients. This validated tool aids research by correlating well with symptom improvements and treatment outcomes.

Area of Science:

  • Urology
  • Clinical Pharmacology
  • Psychometrics

Background:

  • Urinary urgency is a primary, bothersome symptom of overactive bladder (OAB).
  • Assessing perceived urinary urgency is crucial for evaluating OAB treatments.
  • The Urgency Perception Scale (UPS) was developed for this purpose.

Purpose of the Study:

  • To validate the Urgency Perception Scale (UPS) for measuring perceived urinary urgency.
  • To assess the responsiveness of the UPS to treatment in OAB patients.

Main Methods:

  • Secondary analysis of data from three clinical trials of tolterodine for OAB.
  • Construct validity assessed via correlations with voiding diary variables and other patient-reported outcomes.
  • Evaluated correlations with bladder condition perception, treatment benefit, SF-36, King's Health Questionnaire, OAB Questionnaire, and Overall Treatment Effect scale.

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Main Results:

  • The UPS demonstrated good construct validity, correlating significantly with bladder condition perception (r=-0.29 to -0.46, P<0.001).
  • UPS scores correlated with voiding diary variables, including incontinence episodes (r=-0.30 to -0.41, P<0.001) and pad usage (r=-0.25 to -0.38, P<0.001).
  • Improvements in UPS scores at treatment end corresponded with significant improvements in all voiding diary variables.

Conclusions:

  • The Urgency Perception Scale (UPS) is a valid subjective measure of urinary urgency.
  • The UPS is a valuable research tool for assessing urinary urgency in OAB.
  • Urinary urgency significantly impacts daily life due to its unpredictability.