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Updated: Aug 19, 2026

Establishment of a Rat Model for Intrauterine Adhesions via Dual Injury: Curettage and Infection
Published on: October 3, 2025
Adhesion formation and intraperitoneal catheters: histologic findings in a rat model
George C Zografos1, Kreon M Simeonidis, Evangelos G Messaris
11st Propaedeutic Surgical Clinic, University of Athens, Hippokrateio Hospital, Athens, Greece.
Abstract:
Pieces of polyurethane, Teflon, silicone, and polyvinyl chloride were placed intraperitoneally to compare the histologic findings regarding intraperitoneal adhesion development in a rat model. The overall adhesion score differed significantly among the groups, the highest being in the Teflon group (mean 13.2), followed in descending order by the polyvinyl chloride group (10), the silicone group (9.6), and the polyurethane group (6.8). Thus, polyurethane causes the least adhesion development and can be used more extensively for the construction of catheters for intraperitoneal use.

