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[Study on experimental factors for extraction of alkaloids from Aconitum carmichaili]
1Pharmaceutical Department, People's Hospital of Hezhou, Hezhou 542800, China.
Objective:
To determine the suitable conditions for extracting alkaloidals from Aconitum carmichaili.
Method:
Using methods in Chinese Pharmacopeia for determining yields of extraction, which include spectrometry and single-factor tests, we investigated vavious factors that would affect the extraction of alkaloids from Aconiti.
Result:
The suitable extractant was 85% ethanol, starting material was medium-size powder of aconiti, 10 times of the volume of the solvent was used in extraction for twice 1.75 h each time. The extraction yield was 1.21%, with a content of 0.33% alkaloids.
Conclusion:
Extraction conditions determined with single factor test was consistent and feasible.
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