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Gastrostomy tube feeding in children with cerebral palsy: a prospective, longitudinal study
Peter B Sullivan1, Edmund Juszczak, Allison M E Bachlet
1University of Oxford, Department of Paediatrics, Oxford, UK. peter.sullivan@paediatrics.ox.ac.uk
Insights
Gastrostomy tube feeding significantly improved weight and health in children with cerebral palsy (CP), reducing feeding time and complications. This intervention offers a vital solution for nutritional support in this population.
Area of Science:
- Pediatric Gastroenterology
- Neurology
- Clinical Nutrition
Background:
- Children with cerebral palsy (CP) often face significant challenges with growth and nutritional intake.
- Many children with CP experience severe feeding difficulties, impacting their overall health and development.
- Gastrostomy tube feeding is a potential intervention to address these nutritional deficits.
Purpose of the Study:
- To prospectively evaluate the outcomes of gastrostomy tube feeding in children with cerebral palsy.
- To assess changes in growth, nutritional status, general health, and complications associated with gastrostomy feeding.
- To determine the impact of gastrostomy feeding on feeding time and parental-reported health improvements.
Main Methods:
- A longitudinal, prospective, multicentre cohort study involving 57 children with CP.
- Children were assessed at baseline, 6 months, and 12 months post-gastrostomy tube placement.
- Outcome measures included anthropometry, nutritional intake, general health, and complication monitoring.
Main Results:
- Significant increases in median weight z scores were observed, from -3 at baseline to -1.6 at 12 months.
- Almost all parents reported substantial improvements in their child's health and a reduction in feeding time.
- Clinically important increases in weight gain and subcutaneous fat deposition were noted, with rare serious complications.
Conclusions:
- Gastrostomy tube feeding is an effective intervention for improving nutritional status and overall health in children with cerebral palsy.
- The procedure leads to significant weight gain and enhanced general health with a low risk of serious complications.
- Gastrostomy feeding offers a valuable solution for managing feeding difficulties and improving quality of life for children with CP and their families.
Abstract:
We report a longitudinal, prospective, multicentre cohort study designed to measure the outcomes of gastrostomy tube feeding in children with cerebral palsy (CP). Fifty-seven children with CP (28 females, 29 males; median age 4y 4mo, range 5mo to 17y 3mo) were assessed before gastrostomy placement, and at 6 and 12 months afterwards. Three-quarters of the children enrolled (43 of 57) had spastic quadriplegia; other diagnoses included mixed CP (6 of 57), hemiplegia (3 of 57), undiagnosed severe neurological impairment (3 of 57), ataxia (1 of 57), and extrapyramidal disorder (1 of 57). Only 7 of 57 (12%) could sit independently, and only 3 of 57 (5%) could walk unaided. Outcome measures included growth/anthropometry, nutritional intake, general health, and complications of gastrostomy feeding. At baseline, half of the children were more than 38D below the average weight for their age and sex when compared with the standards for typically-developing children. Weight increased substantially over the study period; the median weight z score increased from -3 before gastrostomy placement to -2.2 at 6 months and -1.6 at 12 months. Almost all parents reported a significant improvement in their child's health after this intervention and a significant reduction in time spent feeding. Statistically significant and clinically important increases in weight gain and subcutaneous fat deposition were noted. Serious complications were rare, with no evidence of an increase in respiratory complications.
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