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Rapid Determination of the Thermal Nociceptive Threshold in Diabetic Rats
Published on: May 17, 2012
Antinociceptive effect of Teucrium polium leaf extract in the diabetic rat formalin test
Tourandokht Baluchnejadmojarad1, Mehrdad Roghani, Farshad Roghani-Dehkordi
1Department of Physiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Abstract:
This study was designed to evaluate the analgesic effect of Teucrium polium leaf extract in the diabetic rat formalin test. For this purpose, streptozotocin (STZ)-diabetic rats received intraperitoneal injection of this extract (100 and 200 mg/kg per day) for a period of 2 weeks. It was found out that Teucrium polium-treated diabetic rats exhibited a lower nociceptive score as compared to untreated diabetics. The results may suggest therapeutic potential of Teucrium polium extract for the treatment of diabetic hyperalgesia.

