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Updated: Aug 19, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Microvascular angina, adverse outcome: a case report
Akira Nakano1, Jong-Dae Lee, Hiromasa Shimizu
1First Department of Internal Medicine, Fukui Medical University, Matsuoka-cho, 23-3 Shimoaizuki, Fukui 910-1193, Japan.
Abstract:
We encountered a patient with microvascular angina (MVA) who was died suddenly, and observed ST-segment elevation during attack without epicardial coronary arterial vasoconstriction, suggesting the occurrence of microvascular spasm. Doppler guide wire (DGW) and N-13 ammonia positron emission tomography (PET) demonstrate severe impairment of the coronary microcirculation extending throughout the whole of the left ventricle. Conventional medical treatment was not effective in this case. We speculate that the prognosis of microvascular angina with severe coronary microcirculatory disturbance and accompanied by microvascular spasm might not always be good. Therefore, methods for treating such cases need to be established.
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