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An Ex vivo Model of an Oligodendrocyte-directed T-Cell Attack in Acute Brain Slices
Published on: February 5, 2015
Astrocytoma-like multiple sclerosis
E E Pakos1, P G Tsekeris, K Chatzidimou
1Department of Radiation Therapy, School of Medicine, University Hospital of Ioannina, University of Ioannina, Ioannina 45500, Greece. emilpak@yahoo.gr
Abstract:
Multiple sclerosis (MS) may sometimes mimic clinically and radiologically a brain tumor. The initial recognition of such cases is essential as it might avoid a surgical intervention and supplementary treatment. However, even in patients who underwent surgery, the appropriate preparation of the specimen is of crucial importance for the correct pathological diagnosis since tumors and non-neoplastic demyelinating lesions share some common histopathological features. We present such a case of multiple sclerosis presenting with features of an astrocytoma and was treated with surgery and additional radiotherapy.
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