Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The case for open-source software in drug discovery.

Warren L DeLano1

  • 1DeLano Scientific LLC, 400 Oyster Point Blvd., Suite 213, San Francisco, CA 94080, USA.

Drug Discovery Today
|February 15, 2005
PubMed
Summary

Open-source software is increasingly successful beyond niche uses. Drug discovery consumers will benefit from flexible, complementary open-source products.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hot-spot mimicry of a cytokine receptor by a small molecule.

Proceedings of the National Academy of Sciences of the United States of America·2006
Same author

Identification of potent and novel small-molecule inhibitors of caspase-3.

Bioorganic & medicinal chemistry letters·2003
Same author

Discovery of a potent small molecule IL-2 inhibitor through fragment assembly.

Journal of the American Chemical Society·2003
Same author

Binding of small molecules to an adaptive protein-protein interface.

Proceedings of the National Academy of Sciences of the United States of America·2003
Same author

In situ assembly of enzyme inhibitors using extended tethering.

Nature biotechnology·2003
Same author

Identification of potent and selective small-molecule inhibitors of caspase-3 through the use of extended tethering and structure-based drug design.

Journal of medicinal chemistry·2002

Area of Science:

  • Computer Science
  • Bioinformatics
  • Drug Discovery

Background:

  • Open-source software (OSS) is widely adopted in various tech sectors, including network infrastructure, web servers, code development, and operating systems.
  • The pervasive success raises questions about the future scope and limitations of OSS adoption.
  • Understanding the drivers of OSS success is crucial for predicting its expansion into new domains.

Purpose of the Study:

  • To identify the key factors contributing to the widespread success of open-source software.
  • To predict the future impact and benefits of open-source products within the drug discovery sector.
  • To explore how open-source solutions can complement existing proprietary options in pharmaceutical research.

Main Methods:

  • Analysis of the factors driving open-source software adoption and success.
  • Forecasting potential applications and benefits of open-source tools in drug discovery.
  • Evaluation of the complementary nature of open-source products alongside proprietary software.

Main Results:

  • Open-source software has demonstrated significant success and adoption beyond its traditional niche markets.
  • Several factors contribute to the growing prevalence and effectiveness of open-source solutions.
  • New open-source products are emerging that offer enhanced flexibility for drug discovery processes.

Conclusions:

  • Open-source software adoption is likely to expand further, moving beyond hobbyist and hacker communities.
  • Drug discovery consumers stand to gain substantial benefits from the increased flexibility and complementary nature of new open-source products.
  • The integration of open-source tools promises to enhance efficiency and innovation in pharmaceutical research and development.

Related Experiment Videos