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Psoriasis treatment: traditional therapy.
M Lebwohl1, P T Ting, J Y M Koo
1The Mount Sinai School of Medicine, New York, NY, USA. lebwohl@aol.com
Annals of the Rheumatic Diseases
|February 15, 2005
Summary
Psoriasis treatment options include topical therapies for localized skin issues, phototherapy for widespread disease, and systemic medications for severe or resistant cases. These established treatments offer effective management for psoriasis patients.
Area of Science:
- Dermatology
- Immunology
Background:
- Psoriasis is a chronic inflammatory skin condition.
- Effective treatments have long been available, predating biological agents.
Purpose of the Study:
- To review established psoriasis treatment modalities.
- To categorize treatments based on disease severity and location.
Main Methods:
- Review of existing literature on psoriasis therapies.
- Classification of treatments into topical, phototherapy, and systemic categories.
Main Results:
- Topical therapies (corticosteroids, vitamin D analogues, retinoids) are effective for localized psoriasis.
- Phototherapy (UVB, PUVA, climatotherapy) benefits patients with extensive skin involvement.
- Systemic agents (methotrexate, retinoids, ciclosporin) manage refractory or widespread cutaneous disease.
Conclusions:
- A range of non-biological treatments effectively manages psoriasis.
- Treatment selection depends on disease extent and refractoriness.