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Updated: Aug 19, 2026
An Efficient and Rapid HPLC-QQQ-MS Method for the Quantitation of Tropane Alkaloids in Medicinal Plants
Published on: June 12, 2026
[The new secondary metabolite from Polygonatum odoratum]
Hai-lin Qin1, Zhi-hong Li, Peng Wang
1Instiute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China. qinhailin@imm.ac.cn
Objective:
To investigate the chemical constituents of Polygonatum odoratum.
Method:
Silica gel column chromatography was used to separate and purify the chemical constituents. The structures were elucidated by chemical and spectral analysis.
Result:
One dipeptide and one furostanol glycoside were isolated from the rhizomes of P. odoratum, and their structures were identified as O-acetate of N (N-benzoyl-S-phenylalaninyl)-S-phenylalaninol (1) and 22-hydroxy-25 (R and S)-furost-5-en-12-on-3beta,22,26-triol 26-O-beta-D-glucopyranoside (2), respectively.
Conclusion:
Compound (2) is a new compound and is first reported to be of the furostanol monoglycoside glycosylated at C-26.
