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Updated: Aug 19, 2026

Simple In-House Ultra-High Performance Capillary Column Manufacturing with the FlashPack Approach
Published on: December 4, 2021
[Technique and application for packing preparative liquid chromatographic column by dynamic axial compression]
Jinyu Han1, Wenying Wei, Heying Chang
1Key Laboratory for Green Chemical Technology of State Education Ministry, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, China. hanjinyu@eyou.com
Abstract:
The theory, installation, and installation design conditions for packing liquid chromatographic column by dynamic axial compression (DAC) are reviewed with 50 references cited. The effects of column length, the properties of packing materials, the properties of slurring solvents, and the pressure of compression on packing process and column performances are analyzed. The problems on density non-homogeneity in the column and the effect of column wall, and the methods for solving them are presented. The advantages and disadvantages of this technique, its applications, current state of development, and perspectives are discussed.
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