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Cryptococcemia. An analysis of 28 cases with emphasis on the clinical outcome and its etiologic agent
Alessandro Comarú Pasqualotto1, Cecília Bittencourt Severo, Flávio de Mattos Oliveira
1Infection Control Department, Micology Laboratory, Santa Casa Complexo Hospitalar, Porto Alegre, Brazil. pasqualotto@santacasa.tche.br
Abstract:
Clinical protocols of 28 cases of cryptococcemia studied between April 1995 and November 2002 were reviewed. The varieties of Cryptococcus neorformans, the underlying disease, and the severity and outcome of the disease were emphasized. Most patients were immunossupressed (89.3% with AIDS) and Cryptococcus neoformans var. grubii was the main recovered variety (92.8%). Regardless of antifungal treatment, in-hospital mortality was 41% strongly associated with APACHE II score, >14 (p<0.01).
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