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[Coronary risk differences in hypertensive patients of different autonomous communities. CORONARY study]

J Cosín Aguilar1, L Rodríguez Padial, J L Zamorano Gómez

  • 1Hospital Universitario La Fe, Valencia. hernandiz_amp@gva.es

Revista Clinica Espanola
|February 16, 2005
PubMed

Insights

Hypertensive patients in Spain's south-east regions face higher coronary event risk compared to the north. However, the risk of fatal cardiovascular events remains consistent across regions.

Area of Science:

  • Cardiology
  • Public Health
  • Epidemiology

Background:

  • Regional variations in cardiovascular morbidity and mortality exist across Spanish Autonomous Communities (SACs).
  • Understanding these variations in hypertensive patient populations is crucial for targeted interventions.

Purpose of the Study:

  • To investigate regional differences in cardiovascular risk among hypertensive patients in Spain.
  • To compare the 10-year risk of coronary events and fatal cardiovascular events across different SACs.

Main Methods:

  • A cohort of 6,775 hypertensive patients (blood pressure ≥ 140/90 mmHg with at least one other risk factor) was studied.
  • Data was collected from 1,720 family physicians across 17 SACs.
  • Coronary event (CE) risk (Framingham equation) and fatal cardiovascular event (RCV) risk (Score formula) were calculated.

Main Results:

  • Patients in south-east SACs had a significantly higher 10-year risk of coronary events (18.8% primary prevention, 26.1% secondary prevention) compared to northern SACs (20.5% primary prevention, 28.6% secondary prevention).
  • These differences persisted even when including diabetic patients.
  • No significant regional differences were observed in the risk of fatal cardiovascular events (8.9% north vs. 8.8% south-east).

Conclusions:

  • Hypertensive populations in south-east SACs exhibit an elevated risk of coronary events compared to northern SACs and the national average.
  • The risk of fatal cardiovascular events does not differ significantly between these regions.
  • These findings highlight the need for geographically tailored cardiovascular risk management strategies.
Abstract

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