Related Experiment Video
Updated: Aug 19, 2026

Studying Murine Small Bowel Mechanosensing of Luminal Particulates
Published on: March 18, 2022
Small intestinal motility
Michael P Jones1, Sarah Wessinger
1Division of Gastroenterology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA. mpjones@nmh.org
Purpose Of Review:
To review recently published studies presenting novel and relevant information on small intestinal motility in humans and animals.
Recent Findings:
The reviewed studies covered a variety of topics with several themes emerging. The relation between bacterial overgrowth and altered intestinal motility gathers support in a variety of conditions including portal hypertension and senescence. The mechanisms of postoperative ileus are becoming better understood. Cannabinoids play an important role in ileus and this further highlights the importance of these compounds in intestinal motility. Luminal impedance appears to be an important tool for investigation of intestinal flow.
Summary:
Small intestinal motility remains an understudied area. Recent publications have shed additional light on myogenic, neural, and hormonal control mechanisms. Novel investigative techniques will likely further improve our understanding.
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