Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Enteric nervous system.

David Grundy1, Michael Schemann

  • 1Department of Biomedical Science, University of Sheffield, UK. D.Grundy@sheffield.ac.uk

Current Opinion in Gastroenterology
|February 16, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Fennel Tea Has a Region-Specific Effect on the Motility of the Stomach.

Neurogastroenterology and motility·2025
Same author

A Review of the Mechanisms of Action of the Herbal Medicine, STW 5-II, Underlying Its Efficacy in Disorders of Gut-Brain Interaction.

Neurogastroenterology and motility·2025
Same author

Biopsy samples from patients with irritable bowel syndrome, but not from those with mastocytosis or unspecific gastrointestinal complaints reveal unique nerve activation in all gut regions independent of mast cell density, histamine content or specific gastrointestinal symptoms.

Frontiers in neuroscience·2024
Same author

Mechanisms involved in the muscle relaxing effects of STW 5 in guinea pig stomach.

Neurogastroenterology and motility·2024
Same author

Distension evoked mucosal secretion in human and porcine colon in vitro.

PloS one·2023
Same author

Allergen-free extracts from birch, ragweed, and hazel pollen activate human and guinea-pig submucous and spinal sensory neurons.

Neurogastroenterology and motility·2023
Same journal

Endoscopic techniques to minimize gastroesophageal reflux during peroral endoscopic myotomy.

Current opinion in gastroenterology·2026
Same journal

Postendoscopy esophageal adenocarcinoma and neoplasia: current status and future directions.

Current opinion in gastroenterology·2026
Same journal

The complement system in inflammatory bowel disease: from early observations to emerging frontiers.

Current opinion in gastroenterology·2026
Same journal

Goblet cell-associated antigen passages in health and disease.

Current opinion in gastroenterology·2026
Same journal

Inflammatory bowel diseases 2026: form, function and therapeutic considerations for the epithelial barrier.

Current opinion in gastroenterology·2026
Same journal

Dietary protein as a regulator of colitis and colorectal cancer.

Current opinion in gastroenterology·2026
See all related articles

Recent advances in enteric neurobiology enhance understanding of gastrointestinal disorders. Research highlights neural development, enteric reflexes, and pharmacology, paving the way for new therapeutic strategies.

Area of Science:

  • Neurobiology
  • Gastroenterology

Background:

  • The enteric nervous system (ENS) governs gut function.
  • Understanding ENS development and function is crucial for treating gastrointestinal disorders.

Purpose of the Study:

  • To review recent advancements in enteric neurobiology over the past two years.
  • To highlight key areas of progress and their implications for gastrointestinal health.

Main Methods:

  • Review of over 500 studies focusing on key themes in enteric neurobiology.
  • Analysis of research on neural crest cell development, enteric reflexes, and neuropharmacology.

Main Results:

  • Significant progress in understanding ENS development, particularly concerning Hirschsprung disease.

Related Experiment Videos

  • Emerging therapeutic strategies using neural stem cells for ENS repair.
  • New insights into the multifunctional nature of enteric neurons and their regulation by mechanical forces.
  • Advancements in neuropharmacology revealing molecular mechanisms of neuronal excitability and their role in GI disorders.

    • Conclusions:

    • Recent basic science findings offer crucial insights into the pathophysiology of gastrointestinal disorders.
    • This knowledge will improve the understanding and treatment of both organic and functional GI conditions.