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Related Experiment Videos

Correlation between 2 interstitial cystitis symptom instruments.

Erenee Sirinian1, Kathryn Azevedo, Christopher K Payne

  • 1Stanford University Medical Center, Stanford, California, USA.

The Journal of Urology
|February 16, 2005
PubMed
Summary
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This study compared interstitial cystitis (IC) symptom instruments, finding strong correlations between the University of Wisconsin (UWI) and O'Leary-Sant (ICSI/ICPI) tools for IC patients. Wording adjustments may improve symptom-problem pair correlations.

Area of Science:

  • Urology
  • Clinical Research
  • Patient-Reported Outcomes

Background:

  • Interstitial cystitis (IC) is a complex condition requiring validated symptom assessment tools.
  • Previous research utilized distinct instruments for evaluating IC symptoms and their impact.
  • Direct comparison of widely used IC symptom instruments was lacking.

Purpose of the Study:

  • To conduct the first direct comparison between the University of Wisconsin Symptom Instrument (UWI) and the O'Leary-Sant instruments (IC Symptom Index [ICSI] and IC Problem Index [ICPI]).
  • To assess the correlation and agreement between these validated instruments in a clinical population of IC patients.

Main Methods:

  • 107 patients diagnosed with IC were recruited from a urology clinic.
  • Participants completed the ICSI, ICPI, and UWI symptom instruments.

Related Experiment Videos

  • Statistical analysis and graphical representation were used to compare scores.
  • Main Results:

    • Strong correlations were observed between UWI and ICSI (r=0.80) and between ICSI and ICPI (r=0.83).
    • Urgency, nocturia, pain, and frequency showed varying degrees of correlation between symptom severity and problem impact.
    • The symptom of urgency demonstrated the highest correlation with its associated problem (r=0.84).

    Conclusions:

    • The ICSI and UWI instruments show significant correlation in a large IC patient cohort, aiding literature interpretation.
    • Potential wording discrepancies in the O'Leary-Sant instruments may affect the correlation of pain-related symptom-problem pairs.
    • Revising wording in ICSI/ICPI to include parallel phrases like "burning, pain, discomfort or pressure" could enhance correlation and clinical accuracy.