Related Experiment Video

Updated: Aug 19, 2026

Induction and Validation of Cellular Senescence in Primary Human Cells
08:18

Induction and Validation of Cellular Senescence in Primary Human Cells

Published on: June 20, 2018

Interleukin-8 expression is increased in senescent prostatic epithelial cells and promotes the development of benign

Steven A Kaplan

    The Journal of Urology
    |February 16, 2005
    PubMed
    Abstract

    No abstract available in PubMed .

    More Related Videos

    A Quantitative Measurement of Reactive Oxygen Species and Senescence-associated Secretory Phenotype in Normal Human Fibroblasts During Oncogene-induced Senescence13:59

    A Quantitative Measurement of Reactive Oxygen Species and Senescence-associated Secretory Phenotype in Normal Human Fibroblasts During Oncogene-induced Senescence

    Published on: August 12, 2018

    A Mouse Model to Investigate the Role of Cancer-Associated Fibroblasts in Tumor Growth06:35

    A Mouse Model to Investigate the Role of Cancer-Associated Fibroblasts in Tumor Growth

    Published on: December 22, 2020

    Related Concept Videos

    Receptor Downregulation in MVBs01:15

    Receptor Downregulation in MVBs

    Multivesicular bodies (MVBs) are mature endosomes that sort ubiquitinated proteins and then fuse with lysosomes to degrade the sorted proteins. Epidermal growth factor (EGF) and its receptor (EGFR) form a complex that can be internalized through endocytosis, sorted into an MVB, and later degraded.
    The EGFR can initiate signaling pathways that  lead to cell proliferation, migration, and differentiation. Overexpression of EGFR  stimulates cells to proliferate. Excessive  EGFR activation may...