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High-resolution two-dimensional echocardiography improves the quantification of left ventricular function.

G Görge1, R Erbel, R Brennecke

  • 1II. Medical Clinic, University Hospital, Mainz, Federal Republic of Germany.

Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography
|March 1, 1992
PubMed
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Newer two-dimensional echocardiography accurately measures left ventricular ejection fraction, overcoming previous underestimations compared to cineventriculography. This advanced echo technology improves cardiac volume assessment.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Echocardiography

Background:

  • Previous echocardiography techniques often underestimated left ventricular volumes and ejection fraction compared to cineventriculography (CVG).
  • Advancements in ultrasound technology may improve the accuracy of echocardiographic measurements.

Purpose of the Study:

  • To evaluate if state-of-the-art, high-resolution two-dimensional echocardiography (2D echo) prevents the underestimation of ejection fraction (EF) when compared to CVG.
  • To compare current 2D echo accuracy with historical data from 1983.

Main Methods:

  • 48 patients underwent high-resolution 2D echo using a 3.5 MHz transducer prior to CVG.
  • Left ventricular volumes and EF were calculated using the biplane method of discs.
  • Data from 1990 were compared with previously published data from 1983 (37 patients).

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Main Results:

  • In the 1990 study, differences between 2D echo and CVG were not significant for end-diastolic volume (4.7 ml/m2/BSA), end-systolic volume (0.1 ml/m2), and EF (1.5%).
  • In contrast, the 1983 study showed significant underestimation by 2D echo: -39.1 ml/m2/BSA for end-diastolic volume, -17.4 ml/m2 for end-systolic volume, and -7.2% for EF (all p < 0.001).
  • Regression analysis showed improved correlation (r=0.935) in the 1990 study compared to 1983 (r=0.803).

Conclusions:

  • State-of-the-art, high-resolution 2D echocardiography effectively prevents the systematic underestimation of left ventricular volumes and ejection fraction.
  • Improved endocardial delineation in end-systole likely contributes to the enhanced accuracy of modern echocardiography.