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Related Experiment Videos

Bednar tumor.

Sarah Kuruvila1, Fatma A Ramadan

  • 1Department of Histopathology, Royal Hospital, PB No. 1331, PC 111, Seeb, Muscat, Sultanate of Oman. alexp@omantel.net.com

Saudi Medical Journal
|February 16, 2005
PubMed
Summary
This summary is machine-generated.

Pigmented dermatofibrosarcoma protuberance (DFSP), also known as Bednar tumor, is a rare skin cancer variant. Its unique histology features melanin-laden cells and characteristic spindle cells, making it microscopically striking.

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Area of Science:

  • Dermatopathology
  • Oncology
  • Histology

Background:

  • Pigmented dermatofibrosarcoma protuberance (DFSP), or Bednar tumor, is a rare variant of DFSP.
  • First described by Bednar in 1957, this tumor presents unique histological features.

Observation:

  • The striking histology includes multipolar, pigment-laden dendritic cells.
  • These cells are interspersed with spindle-shaped cells arranged in a storiform pattern, typical of DFSP.

Findings:

  • Immunohistochemistry reveals spindle cells are positive for CD34 and Vimentin.
  • The spindle cells are negative for S100, and the pigment is confirmed as melanin.

Implications:

  • This case highlights the rarity and distinct microscopic appearance of pigmented DFSP.
  • Understanding these features is crucial for accurate diagnosis and classification of rare skin tumors.