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Daflon for haemorrhoids: a prospective, multi-centre observational study
1Department of Surgery, Dammam Central Hospital, Dammam, Eastern Province, Saudi Arabia. meshikhes@doctor.com
Summary
Daflon effectively alleviates hemorrhoidal symptoms like pain and bleeding. This study shows significant improvement in patient-reported symptoms and proctoscopic appearance after four weeks of treatment.
Area of Science:
- Gastroenterology
- Vascular Medicine
Background:
- Daflon is a phlebotropic agent with established efficacy in venous disorders.
- Its effectiveness in managing hemorrhoidal symptoms requires further assessment.
Purpose of the Study:
- To confirm the efficacy of Daflon in alleviating various hemorrhoidal symptoms.
- To evaluate Daflon's impact on the proctoscopic appearance of hemorrhoids.
Main Methods:
- A multicenter, non-randomized observational study involving 268 patients with hemorrhoidal symptoms.
- Patients received four Daflon tablets daily for four weeks.
- Symptom assessment and proctoscopy were performed at baseline and weekly intervals.
Main Results:
- Statistically significant improvement was observed in all assessed hemorrhoidal symptoms (pain, heaviness, bleeding, pruritus, anal discharge) (p<0.001).
- Proctoscopic appearance of hemorrhoids showed significant improvement after four weeks of Daflon treatment.
Conclusions:
- Daflon demonstrates efficacy in alleviating hemorrhoidal symptoms and improving their proctoscopic appearance.
- It is a potential initial treatment option for patients with hemorrhoidal symptoms.
- Further randomized trials and longer follow-up are recommended to define Daflon's role in hemorrhoidal disease management.