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Explaining the 2001-02 infant mortality increase: data from the linked birth/infant death data set
Marian F MacDorman1, Joyce A Martin, T J Mathews
1Division of Vital Statistics, Centers for Disease Control and Prevention, National Center for Health Statistics, 3311 Toledo Road, Hyattsville, Maryland 20782, USA.
Insights
The U.S. infant mortality rate rose in 2002, the first increase in decades. This rise was primarily driven by more births of infants weighing less than 750 grams, impacting diverse demographic groups.
Area of Science:
- Public Health
- Demography
- Neonatal Research
Background:
- The U.S. infant mortality rate (IMR) saw its first increase in over 40 years, rising from 6.8 to 7.0 deaths per 1,000 live births between 2001 and 2002.
- Increases in IMR were observed for very low birthweight, preterm, and very preterm infants.
Purpose of the Study:
- To analyze the contributing factors to the increase in U.S. infant mortality between 2001 and 2002.
- To investigate the role of changes in birthweight distribution, specifically the rise in births weighing less than 750 grams.
Main Methods:
- Analysis of U.S. birth and death records from 2001-2002.
- Examination of birthweight distribution shifts and their impact on overall infant mortality.
- Evaluation of hypotheses related to reporting changes, risk profiles, and medical management.
Main Results:
- The primary driver of the increased IMR was a shift in birthweight distribution, with a notable rise in infants born weighing less than 750 grams.
- Increased births of infants under 750 grams occurred across non-Hispanic white, non-Hispanic black, and Hispanic women, and among mothers aged 20-34.
- While multiple births contributed, the majority of the increase in very low birthweight infants occurred among singletons.
Conclusions:
- The increase in infant mortality is significantly linked to a rise in births of extremely low birthweight infants (<750g).
- Factors contributing to the increase in <750g births include demographic shifts and potentially changes in medical practices, though further research is needed.
- The complex interplay of factors necessitates more detailed studies to fully understand and address the 2001-2002 infant mortality increase.
Abstract:
The U.S. infant mortality rate increased from 6.8 infant deaths per 1,000 live births in 2001 to 7.0 in 2002, the first increase in more than 40 years. From 2001 to 2002 infant mortality rates increased for very low birthweight infants as well as for preterm and very preterm infants. Although infant mortality rates for very low birthweight infants increased, most of the increase in the infant mortality rate from 2001 to 2002 was due to a change in the distribution of births by birthweight and, more specifically, to an increase in infants born weighing less than 750 grams (1 lb 10 1/2 oz). The majority of infants born weighing less than 750 grams die within the first year of life; thus, these births contribute disproportionately to the overall infant mortality rate. Increases in births at less than 750 grams occurred for non-Hispanic white, non-Hispanic black, and Hispanic women. Most of the increase occurred among mothers 20-34 years of age. Although multiple births contributed disproportionately, most of the increase in births at less than 750 grams occurred among singletons. Three hypotheses were evaluated to assess their possible impact on the increase in less than 750-gram births: first, possible changes in the reporting of births or fetal deaths; second, possible changes in the risk profile of births; and third, possible changes in medical management of pregnancy. Although each of these factors may have contributed to the increase, the relative effects of these and other factors remain unclear. More-detailed studies are needed to further explain the 2001-02 infant mortality increase.
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