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Management of hypertension in older persons
Lori M Dickerson1, Maria V Gibson
1Medical University of South Carolina, Charleston, South Carolina 29406, USA. macfarll@musc.edu
Insights
Antihypertensive therapy benefits older adults, including those over 80, by reducing cardiovascular risks. However, blood pressure control remains a challenge, necessitating careful medication selection based on individual health factors.
Area of Science:
- Gerontology
- Cardiology
- Pharmacology
Background:
- Antihypertensive therapy significantly reduces morbidity and mortality in older adults with elevated blood pressure.
- Despite known benefits, less than one-third of elderly patients achieve adequate blood pressure control.
- Systolic blood pressure is a critical predictor of cardiovascular disease in this demographic.
Purpose of the Study:
- To review the efficacy and challenges of antihypertensive therapy in patients over 80 years old.
- To emphasize the importance of blood pressure management in older populations.
- To guide the selection of antihypertensive medications for elderly patients.
Main Methods:
- Literature review of studies on antihypertensive therapy in older adults.
- Analysis of blood pressure control rates in patients over 80.
- Evaluation of medication classes for treating hypertension in the elderly.
Main Results:
- Antihypertensive therapy demonstrates persistent benefits in patients older than 80.
- Orthostatic hypotension assessment is crucial during blood pressure measurement in older persons.
- Low-dose thiazide diuretics are recommended as first-line treatment.
Conclusions:
- Effective blood pressure management is vital for reducing cardiovascular disease in older adults.
- Second-line agents like beta blockers, ACE inhibitors, ARBs, and CCBs should be chosen based on comorbidities.
- Optimizing antihypertensive strategies is essential for improving health outcomes in the elderly.
Abstract:
Antihypertensive therapy has been shown to reduce morbidity and mortality in older patients with elevated systolic or diastolic blood pressures. This benefit appears to persist in patients older than 80 years, but less than one third of older patients have adequate blood pressure control. Systolic blood pressure is the most important predictor of cardiovascular disease. Blood pressure measurement in older persons should include an evaluation for orthostatic hypotension. Low-dose thiazide diuretics remain first-line therapy for older patients. Beta blockers, angiotensin-converting enzyme inhibitors, angiotensin-receptor blockers, and calcium channel blockers are second-line medications that should be selected based on comorbidities and risk factors.
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