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Tibial angioplasty as an alternative strategy in patients with limb-threatening ischemia
Daniel G Clair1, Rajeev Dayal, Peter L Faries
1Division of Vascular Surgery, New York-Presbyterian Hospital, Columbia College of Physicians and Surgeons and The Weill Cornell Medical School, New York, NY 10032, USA. claird@ccf.org
Insights
Tibial angioplasty is technically feasible for patients with limb-threatening ischemia, offering improved outcomes like pain relief and wound healing. This endovascular approach is a viable option before amputation or high-risk bypass surgery.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Endovascular Therapy
Background:
- Limb-threatening ischemia often presents challenges for surgical revascularization.
- Patients unsuitable for bypass grafting require alternative treatment strategies.
- Tibial angioplasty offers a less invasive option for critical limb ischemia.
Purpose of the Study:
- To evaluate the technical feasibility of tibial angioplasty in patients with limb-threatening ischemia.
- To assess the early clinical outcomes of tibial angioplasty in this patient cohort.
- To determine the safety and efficacy of endovascular treatment for critical limb ischemia.
Main Methods:
- Retrospective analysis of 19 patients undergoing crural angioplasty for limb-threatening ischemia.
- Utilized 0.018- or 0.014-inch guidewire-based systems for angioplasty.
- Concurrent treatment of inflow lesions performed in 12 limbs (angioplasty +/- stenting).
Main Results:
- Technical success achieved in 22 of 23 treated vessels (95.6%).
- Mean ankle-brachial index (ABI) improved from 0.53 to 0.85 post-procedure.
- 16 patients showed improvement with wound healing and pain relief; 3 required amputation.
Conclusions:
- Tibial angioplasty demonstrates high technical success and positive early outcomes for limb-threatening ischemia.
- Endovascular treatment is a justifiable option prior to amputation or high-risk bypass.
- Further studies are needed to determine the long-term durability of tibial angioplasty.
Abstract:
The purpose of this study was to assess the technical feasibility and early outcome of tibial angioplasty for a subset of patients with limb-threatening ischemia who were not candidates for bypass grafting. A retrospective analysis was conducted of 19 patients (7 male, 12 female) who underwent crural angioplasty for limb-threatening ischemia using 0.018- or 0.014 inch-based systems. Contraindications to bypass were insufficient conduit in 7 patients and severe comorbid illness in 12. Concurrent treatment of inflow lesions was performed in 12 of 20 limbs via either angioplasty alone (5) or combined with stenting (12). Outcome measures were ankle-brachial indices (ABI), relief of rest pain, and healing or healed wounds. Twenty-three vessels were treated, including 14 tibial occlusions and 9 stenoses. The average length of diseased segment was 11 cm (range, 3-25 cm). Thirteen of 14 occlusions were treated with subintimal recanalization, the remainder with laser recanalization. Technical success was achieved in 22 of 23 treated vessels. Mean preoperative ABI was 0.53 and mean postoperative ABI was 0.85. Palpable pulses were present in 11 of 20 limbs (55%). There was one perioperative mortality (5.2%). Mean follow-up was 3 months. Three failures occurred requiring amputation (15.8%). The remaining 16 patients were improved with healing (8) or healed (4) wounds and relief of rest pain (4). These results indicate that technical success may be achieved with outflow lesion angioplasty in the majority of patients encountered. The durability of this method of therapy is unknown, and our length of follow-up is not sufficient to answer this question. However, an attempt at angioplasty appears justified before primary amputation and before surgical bypass in those patients at high risk for intervention.
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