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Updated: Aug 19, 2026
High-resolution Tandem Mass Spectrometry for Studying Chemical Constituents of Gynura bicolor DC
Published on: February 2, 2024
[Studies on the chemical constituents in herb of Ranunculus sceleratus]
Xiao-zhong Gao1, Chang-xin Zhou, Shui-li Zhang
1Department of Traditional Chinese Medicine and Natural Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310031, China.
Objective:
To isolate and determine the chemical constituents from Ranunculus sceleratus.
Method:
Six compounds were isolated and purified by extraction and different kinds of column chromatography. The structures were determined on the basis of extensive spectral analysis such as EI-MS, 1H-NMR, 13C-NMR, DEPT and NOEDS.
Result:
The structures were elucidated as stigmasta-4-ene-3,6-dione I, stigmasterol II, isoscopoletin III, scoparone IV, protocatechuic aldehyde V and protocatechuic acid VI, respectively.
Conclusion:
Compound I, III, IV, V and VI were isolated from R. genus for the first time.
