Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Deficient internal models for planning hand-object interactions in apraxia.

Laurel J Buxbaum1, Scott H Johnson-Frey, Megan Bartlett-Williams

  • 1Moss Rehabilitation Research Institute, Korman Research Pavilion, Philadelphia, PA 19141, USA. ibuxbaum@einstein.edu

Neuropsychologia
|February 18, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Novel tool use does not depend on mechanical reasoning: evidence from apraxia.

bioRxiv : the preprint server for biology·2026
Same author

Dissociation between physical reasoning and tool use in individuals with left hemisphere brain damage.

Cortex; a journal devoted to the study of the nervous system and behavior·2026
Same author

Upregulating action semantics with neuromodulation and gesture observation to facilitate verb retrieval in aphasia.

bioRxiv : the preprint server for biology·2026
Same author

Causes and consequences of unawareness (anosognosia) of tool-action errors after left-hemisphere stroke.

bioRxiv : the preprint server for biology·2026
Same author

The cognitive neuropsychology of action semantics: A review.

Cortex; a journal devoted to the study of the nervous system and behavior·2025
Same author

Dissociation between physical reasoning and tool use in individuals with left hemisphere brain damage.

bioRxiv : the preprint server for biology·2025

Ideomotor apraxia (IM) may stem from impaired internal models for action planning. Patients with IM showed deficits in motor imagery, particularly with complex object interactions, correlating with brain lesions.

Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Motor Control

Background:

  • Motor imagery (MI) is crucial for motor planning and internal model function.
  • Ideomotor apraxia (IM) involves deficits in pantomime and imitation of skilled actions.
  • Internal models predict sensory consequences and specify motor commands for actions.

Purpose of the Study:

  • To test the hypothesis that IM arises from deficits in internal models for object-related actions.
  • To investigate the relationship between motor imagery, action execution, and feedback in IM.
  • To identify neural correlates of IM and motor imagery deficits.

Main Methods:

  • Compared motor imagery and object interaction performance in stroke patients with IM, without IM, and healthy controls.

Related Experiment Videos

  • Assessed imagined grasping of objects with varying orientations.
  • Analyzed lesion locations, particularly in the fronto-parietal regions.

    • Main Results:

    • Motor imagery was strongly correlated with pantomime/imitation but poorly with object interaction in IM patients.
    • IM patients showed particular deficits in computationally difficult motor imagery tasks.
    • Lesions in the intraparietal sulcus were more common in IM patients with motor imagery deficits.

    Conclusions:

    • Deficits in internal models for action planning contribute to ideomotor apraxia.
    • IM impacts object-related gesture pantomime, imitation, and learning.
    • The intraparietal sulcus is implicated in motor imagery for hand-object interactions.