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[Irritable bowel syndrome].

B Adam1, T Liebregts, G Holtmann

  • 1Royal Adelaide Hospital, Department of Gastroenterology, Hepatology and General Medicine, University of Adelaide.

Deutsche Medizinische Wochenschrift (1946)
|February 18, 2005
PubMed
Summary
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Irritable Bowel Syndrome (IBS) significantly impacts patients

Area of Science:

  • Gastroenterology
  • Clinical Medicine

Context:

  • Irritable Bowel Syndrome (IBS) is a prevalent gastrointestinal disorder affecting many patients seeking medical care.
  • While not fatal, IBS imposes a considerable burden on individuals, impairing quality of life and incurring societal economic costs.

Purpose:

  • To review the current understanding of IBS pathophysiology, diagnosis, and treatment.
  • To highlight the gap between scientific discovery and clinical application in IBS management.

Summary:

  • Standardized diagnostic criteria (Rome II, DGVS) exist for IBS.
  • Current treatments include lifestyle advice, psychotherapy, and evidence-based medications (herbal, spasmolytics, antidepressants, 5-HT receptor antagonists/agonists).
  • No cure for IBS is available; treatments focus on symptom palliation, with future therapeutic advancements anticipated.

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Impact:

  • Despite progress in understanding IBS, a significant delay exists in translating these findings into improved patient care.
  • Current IBS treatments offer disappointing response rates, emphasizing the need for novel therapeutic strategies.
  • Future research holds promise for developing curative or more effective treatments for IBS patients.