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Published on: April 20, 2018
Prevention of head and neck cancer
Terry A Day1, Angela Chi, Brad Neville
1Head and Neck Tumor Program, Hollings Cancer Center, Medical University of South Carolina, 96 Jonathan Lucas Street, Charleston, SC 29425, USA. dayt@musc.edu
Abstract:
In the vast majority of cases, head and neck cancer is a preventable disease. The relationship between tobacco and alcohol and these cancers is well established. Despite efforts aimed at reduction of risk factor exposure and early detection methods, head and neck cancer remains one of the more common cancers worldwide. Recent advances in molecular techniques have provided a framework for future targets for early diagnosis and treatment of these malignancies. This review provides a summary of recent developments in primary and secondary prevention of head and neck cancer and innovative strategies aimed at a reduction in incidence and mortality from this disease. The future prevention of head and neck cancer will likely require solutions to the widespread use of tobacco products and innovative diagnostic techniques leading to improvements in overall survival.
Insights
Head and neck cancer is largely preventable, primarily linked to tobacco and alcohol use. Future prevention strategies focus on reducing risk factors and improving early detection through molecular advancements to decrease incidence and mortality.
Area of Science:
- Oncology
- Public Health
Background:
- Head and neck cancer is a common malignancy with well-established links to tobacco and alcohol consumption.
- Despite prevention and early detection efforts, head and neck cancer incidence remains high globally.
Purpose of the Study:
- To review recent advancements in primary and secondary prevention of head and neck cancer.
- To explore innovative strategies for reducing head and neck cancer incidence and mortality.
Main Methods:
- Literature review of recent developments in head and neck cancer prevention.
- Analysis of molecular techniques for early diagnosis and treatment targets.
Main Results:
- Head and neck cancers are predominantly preventable, with strong etiological links to tobacco and alcohol.
- Molecular techniques offer new avenues for early diagnosis and targeted therapies.
- Current prevention and detection methods require enhancement to significantly reduce global burden.
Conclusions:
- Future head and neck cancer prevention hinges on addressing widespread tobacco use.
- Innovative diagnostic tools are crucial for improving patient survival rates.
- Integrated strategies combining risk reduction and advanced diagnostics are essential.
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