Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Calcium-sensing receptor expression in human adipocytes.

Mariana Cifuentes1, Cecilia Albala, Cecilia Rojas

  • 1Institute of Nutrition and Food Technology, University of Chile, Macul, Casilla, Santiago, Chile. mcifuentes@inta.cl

Endocrinology
|February 19, 2005
PubMed
Summary

The calcium-sensing receptor (CaSR) is expressed in human fat cells and their precursors. This finding introduces a new area for research into adipose tissue biology and CaSR

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Ealth, life satisfaction, and personal well-being of elderly fishermen in Chile].

Revista espanola de geriatria y gerontologia·2026
Same author

Designing a communication strategy to promote Alzheimer's disease prevention: The CULTIVAMENTE campaign.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

Association Between Metabolic and Endocrine Parameters With Visceral Adiposity Index-Defined Adipose Tissue Dysfunction in Young Adult Males.

Journal of obesity·2026
Same author

Willing, but unequally: Indigenous identity influences participation in Alzheimer's disease biomarker research in Chile.

Alzheimer's & dementia (Amsterdam, Netherlands)·2026
Same author

A Health Communication Strategy to Promote Dementia Risk Reduction: The CULTIVAMENTE Pragmatic Cluster-Randomized Trial.

Journal of the American Geriatrics Society·2025
Same author

Public Health.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025

Area of Science:

  • Endocrinology
  • Adipose Tissue Biology
  • Calcium Homeostasis

Background:

  • The calcium-sensing receptor (CaSR) is crucial for systemic calcium homeostasis.
  • Emerging evidence shows CaSR in tissues unrelated to calcium regulation, suggesting broader functions.
  • CaSR influences cell proliferation, differentiation, and apoptosis.

Purpose of the Study:

  • To investigate the expression of CaSR in human omental adipose tissue.
  • To determine if CaSR is present in isolated human adipocytes and adipocyte progenitor cells.

Main Methods:

  • Reverse transcription-polymerase chain reaction (RT-PCR) was used to assess gene expression.
  • Immunoblotting was employed to detect protein presence.

Main Results:

Related Experiment Videos

  • CaSR expression was confirmed in human omental adipose tissue.
  • CaSR was detected in isolated human adipocytes.
  • CaSR expression was also identified in human adipocyte progenitor cells.

Conclusions:

  • This study provides the first evidence of CaSR expression in human adipocytes and progenitor cells.
  • The presence of CaSR in adipose tissue opens new avenues for research into its physiological roles.
  • This discovery contributes a novel component to the understanding of adipose tissue biology.