Single pass aspiration biopsy for repeat sampling--evaluation in 726 cases: technical note.

Fine-needle aspiration (FNA) is widely used for diagnostic sampling of lesions. Standard FNA methods often require multiple needle insertions to obtain sufficient material, increasing procedural time and patient discomfort. Prior research has shown that inadequate sample quality can lead to false-negative results or the need for repeat procedures. No prior work had resolved the issue of visually assessing sample adequacy before needle withdrawal. This gap motivated the development of a single-pass technique. The technique aims to reduce the number of needle insertions while maintaining diagnostic accuracy. It has been proposed that visual feedback during sampling could improve sample quality. However, the effectiveness of such a method had not been systematically evaluated in a large cohort. This paper addresses that uncertainty by analyzing 726 cases.

The study aimed to evaluate a novel single-pass aspiration biopsy technique for fine-needle aspiration. It sought to determine whether this method could reduce the need for multiple needle insertions while maintaining diagnostic accuracy. The specific problem addressed was the challenge of obtaining sufficient and adequate samples in a single pass. The motivation was to improve patient comfort and reduce procedural time. The study also aimed to assess the rate of inadequate material and false-negative results using this new approach. It compared the single-pass method to standard FNA techniques. The goal was to establish whether visual feedback during sampling could enhance sample adequacy. The study focused on lesions in various anatomical regions to test the method's versatility.

The single-pass aspiration biopsy technique was applied to 726 lesions across multiple anatomical regions. The method involved a single needle insertion followed by repeated sampling in one pass. The aspirated material was visually assessed for adequacy before needle withdrawal. Standard FNA procedures served as the control for comparison. Lesions were selected based on clinical suspicion and imaging findings. The study recorded the number of needle insertions and sample adequacy. Outcomes were categorized as adequate, inadequate, or false-negative. The method was tested in both superficial and deep-seated lesions to evaluate its effectiveness.

The single-pass technique achieved a 7.3% rate of inadequate material and a 2.5% false-negative rate across 726 cases. These rates were comparable to or better than standard FNA methods. The technique allowed for immediate visual assessment of sample quality. No significant increase in complications was observed compared to conventional methods. The method was effective in both superficial and deep-seated lesions. The study found that the single-pass approach reduced the number of needle insertions required. It demonstrated a high success rate in obtaining diagnostic samples in one pass. The results suggest that the technique could improve procedural efficiency and patient comfort.

The authors propose that the single-pass aspiration biopsy technique offers a practical alternative to standard FNA methods. They suggest that the ability to assess sample adequacy before needle withdrawal is a key advantage. The technique may reduce the need for multiple insertions while maintaining diagnostic accuracy. The study supports the use of this method in both superficial and deep-seated lesions. The authors suggest that the low complication rate and high success rate make it a viable option. They propose that the technique could be particularly useful in challenging anatomical regions. The findings suggest that the method is effective across a wide range of clinical scenarios. The authors conclude that the single-pass approach is a valuable addition to the diagnostic cytopathology toolkit.