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[Study on chromatogrqphic fingerprint of qingying injection]
Wen-yu Feng1, Hua-rong Qiu, Ji Tian
1Pharmacy Research Institute of Luzhou Medical College, Luzhou 646000, China.
Objective:
To establish the fingerprint detecting standard of Qingyin injection.
Method:
By adopting GC and HPLC, camphor and chlorogenic acid were used as reference material. To analyze separately Qingyin injection which contains volatile and non-volatile chemials. According to the technical requirements of fingerprint on Injection of Chinese traditional medicine, we calculated their bn relative retention time and area proportionality of peaks to determine the common peaks of fingerprint.
Result:
On the basis of systematic methodalogy, we tested and analyzed 13 batches of sample injection so as to establish GC and HPLC fingerprint of the injection.
Conclusion:
15 common peaks on GC and 6 common peaks as well as their retention time and area proportionality on HPLC can be used as the important parameters of the quality control for Qingyin injection.
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