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Madelung's disease.

Chih-Chieh Chuang¹, Yen-Fu Cheng, Hsin-Pin Chang

¹Taipei Municipal Yang-Ming Hospital, Taipei, Taiwan, ROC.

Journal of the Chinese Medical Association : JCMA

|February 22, 2005

Summary

Madelung's disease, a rare condition causing excess fat deposits, is uncommon in Oriental populations. This case report details a 59-year-old male patient and reviews existing literature on this unusual disorder.

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Area of Science:

Endocrinology
Dermatology
Rare Diseases

Background:

Madelung's disease is a rare, benign condition characterized by symmetrical, diffuse, subcutaneous adipose tissue deposits.
It predominantly affects middle-aged male alcoholics, particularly in Mediterranean regions.
The condition's etiology remains largely undetermined.

Observation:

The case involves a 59-year-old male presenting with Madelung's disease.
The characteristic fat deposits were observed on the suboccipital area, cheeks, neck, shoulders, and upper trunk.
Oriental cases of Madelung's disease are exceptionally rare.

Findings:

The patient's clinical course is described in detail.
The presentation mimicked head and neck malignancy but was confirmed as Madelung's disease.
Literature review highlights the rarity of this condition in Oriental populations.

Implications:

This report contributes to the limited understanding of Madelung's disease in non-Mediterranean and Oriental demographics.
It underscores the importance of considering Madelung's disease in the differential diagnosis of neck and facial lipodystrophy.
Management remains symptomatic, focusing on conservative removal for cosmetic or clinical reasons.

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