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[Acute diarrheal disease: a public health challenge in Colombia]
Diana Carolina Cáceres1, Eduardo Estrada, Rodrigo DeAntonio
1Instituto Nacional de Salud, Bogotá, Colombia. dcaceres@ins.gov.co
Insights
Rotavirus infection significantly increases the risk of severe diarrhea and dehydration in young Colombian children. Low birth weight and limited breastfeeding are also key risk factors for this condition.
Area of Science:
- Pediatrics
- Infectious Diseases
- Public Health
Background:
- Diarrheal diseases are a major cause of mortality in children under five globally.
- Rotavirus is a leading viral pathogen responsible for severe gastroenteritis in infants and young children.
- Understanding local risk factors is crucial for effective prevention and management strategies.
Purpose of the Study:
- To determine the association between rotavirus infection and diarrhea with dehydration in Colombian children under five.
- To identify specific risk factors contributing to diarrhea with dehydration in this population.
Main Methods:
- A case-control study was conducted in Bogota, Colombia, involving 290 children under five.
- Cases were children hospitalized with acute diarrheal disease (ADD) and dehydration; controls had ADD without dehydration.
- Data on demographics, socioeconomic status, hygiene practices, and health service access were collected via questionnaires.
Main Results:
- Rotavirus infection was significantly associated with diarrhea and dehydration (OR = 3.46).
- Low birth weight (< 2600 g) and breastfeeding for less than three months were identified as significant risk factors (OR = 7.79 and OR = 3.17, respectively).
- Low socioeconomic status, poor hygiene, and lower maternal education were linked to increased dehydration risk.
Conclusions:
- Rotavirus infection plays a critical role in the severity of acute diarrheal disease in Colombian children.
- Ineffective health promotion and disease prevention efforts contribute to the prevalence of diarrhea with dehydration, even with accessible healthcare.
- Targeted interventions addressing socioeconomic factors, hygiene, and nutritional status are needed.
Objectives:
To establish the relationship between rotavirus infection and dehydration from diarrhea in Colombian children under 5 years of age, and to identify risk factors for diarrhea with dehydration.
Methods:
A case-control study was performed in an urban hospital in Bogota, Colombia, between April 2000 and February 2001. The sample was composed of 290 children of both sexes under 5 years of age; of these children, 145 of them were hospitalized for acute diarrheal disease (ADD) with dehydration (cases), and 145 had a diagnosis of ADD but no signs of dehydration (controls). All children underwent a complete physical examination. Mothers responded to a questionnaire containing items on demographic and socioeconomic variables, as well as on knowledge, attitudes, and practices with regard to hygiene, and on access to health services.
Results:
An association was detected between diarrhea with dehydration and the presence of rotavirus in fecal samples (odds ratio [OR] = 3.46; 95% confidence interval [95% CI]: 1.71 to 7.00), birth weight < 2 600 g (OR = 7.79; 95% CI: 3.47 to 18.01), and breastfeeding for less than 3 months (OR = 3.17; 95% CI: 1.66 to 6.13). The risk of having dehydration was associated with low socioeconomic status, poor hygienic practices among the child's family members, and mother's low educational level.
Conclusions:
The ineffectiveness of health promotion and disease prevention activities in a population with easy access to health services set the stage for the appearance of cases of diarrhea with dehydration. Rotavirus infection plays an important role in the severity of ADD among Colombian children.
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