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Published on: September 15, 2023
Comparison of left ventricular diastolic function after on-pump versus off-pump coronary artery bypass grafting
Kenneth K Ng1, Zoran B Popovic, Richard W Troughton
1Department of Cardiology, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Insights
On-pump coronary artery bypass graft (CABG) surgery led to greater improvements in diastolic function, specifically early diastolic filling and myocardial relaxation, compared to off-pump CABG.
Area of Science:
- Cardiology
- Cardiac Surgery
Background:
- Diastolic dysfunction is a common complication after cardiac surgery.
- Coronary artery bypass graft (CABG) surgery is a standard treatment for coronary artery disease.
- Both on-pump and off-pump CABG techniques are used for revascularization.
Purpose of the Study:
- To compare the effects of on-pump versus off-pump CABG on diastolic function.
- To evaluate changes in early diastolic filling and myocardial relaxation post-revascularization.
Main Methods:
- Prospective evaluation of diastolic function in patients undergoing elective CABG.
- Comparison of diastolic function indexes between patients who had on-pump CABG and those who had off-pump CABG.
Main Results:
- Diastolic function improved in both on-pump and off-pump CABG groups.
- Indexes of early diastolic filling demonstrated significantly greater improvement in the on-pump CABG group.
- Myocardial relaxation also showed more substantial improvement following on-pump CABG compared to off-pump CABG.
Conclusions:
- On-pump CABG may offer superior benefits for improving diastolic function compared to off-pump CABG.
- The findings suggest potential differences in myocardial recovery and diastolic performance based on CABG technique.
Abstract:
We evaluated diastolic function in patients who underwent elective revascularization by standard on-pump coronary artery bypass graft (CABG) surgery versus off-pump CABG. Diastolic function improved in both groups, but indexes of early diastolic filling and myocardial relaxation improved more in patients who underwent on-pump than off-pump CABG.

