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Adenovirus associated haematuria
1The Children's Hospital at Westmead, Sydney, Australia.
Archives of Disease in Childhood
|February 23, 2005
Summary
Adenovirus infections in children commonly cause respiratory illness. In immunocompetent children, 18.6% experienced hematuria, with a small percentage showing macroscopic hematuria and upper tract issues.
Area of Science:
- Pediatric infectious diseases
- Virology
- Nephrology
Background:
- Adenovirus is a frequent cause of respiratory infections in pediatric populations.
- Adenovirus is recognized for inducing acute hemorrhagic cystitis, especially in immunocompromised individuals.
Observation:
- This study focused on adenoviral infections in children.
- The incidence of hematuria was evaluated in both immunocompetent and immunosuppressed pediatric patients.
Findings:
- In immunocompetent children with adenovirus infection, 18.6% exhibited hematuria.
- Macroscopic hematuria and upper urinary tract involvement were observed in 2.4% of these infected children.
Implications:
- These findings highlight the potential for adenovirus to cause significant urinary tract complications, including hematuria, in immunocompetent children.
- Understanding these complications is crucial for accurate diagnosis and management of pediatric adenoviral infections.
- Further research may explore specific viral strains or host factors influencing urinary tract involvement.