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Adenovirus associated haematuria

C W Allen1, S I Alexander

  • 1The Children's Hospital at Westmead, Sydney, Australia.

Archives of Disease in Childhood
|February 23, 2005
PubMed

Insights

Adenovirus infections in children commonly cause respiratory illness. In immunocompetent children, 18.6% experienced hematuria, with a small percentage showing macroscopic hematuria and upper tract issues.

Area of Science:

  • Pediatric infectious diseases
  • Virology
  • Nephrology

Background:

  • Adenovirus is a frequent cause of respiratory infections in pediatric populations.
  • Adenovirus is recognized for inducing acute hemorrhagic cystitis, especially in immunocompromised individuals.

Observation:

  • This study focused on adenoviral infections in children.
  • The incidence of hematuria was evaluated in both immunocompetent and immunosuppressed pediatric patients.

Findings:

  • In immunocompetent children with adenovirus infection, 18.6% exhibited hematuria.
  • Macroscopic hematuria and upper urinary tract involvement were observed in 2.4% of these infected children.

Implications:

  • These findings highlight the potential for adenovirus to cause significant urinary tract complications, including hematuria, in immunocompetent children.
  • Understanding these complications is crucial for accurate diagnosis and management of pediatric adenoviral infections.
  • Further research may explore specific viral strains or host factors influencing urinary tract involvement.

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