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Published on: March 14, 2019
[Tibial osteomyelitis following intraosseous infusion: a case report]
Ali Doğan1, Hasan Irmak, Mustafa Harman
1Department of Orthopedics and Traumatology (Ortopedi ve Travmatoloji Anabilim Dali), Medicine Faculty of Yüzüncü Yil University, Van, Turkey. alidogan67@hotmail.com
Insights
Intraosseous infusion in infants can lead to rare complications like Candida albicans osteomyelitis. Prompt diagnosis and antifungal treatment are crucial for recovery.
Area of Science:
- Pediatric Emergency Medicine
- Infectious Diseases
- Pediatric Orthopedics
Background:
- Intraosseous infusion is a critical route for emergency fluid and medication delivery in pediatric patients.
- This method is particularly vital in infants and young children during critical care scenarios.
Observation:
- A 5-month-old infant receiving intraosseous infusion developed localized swelling and hyperemia at the infusion site.
- Clinical examination revealed a fistula with serous discharge, and radiographic imaging showed periosteal reaction and osteolytic lesions in the proximal tibia.
Findings:
- The infant was diagnosed with acute osteomyelitis, confirmed by surgical site cultures yielding Candida albicans.
- Treatment involved surgical drainage, medullary irrigation, parenteral antibiotics, and a four-week course of fluconazole.
Implications:
- This case highlights a rare but serious complication of intraosseous infusion in infants.
- Early recognition, appropriate diagnostic workup, and targeted antifungal therapy are essential for successful management of fungal osteomyelitis in this population.
Abstract:
Fluids, medications, and blood products can be rapidly administered via intraosseous infusion under emergency conditions, particularly to pediatric patients aged from 0 to 2 years. A five-month-old infant who had been hospitalized with a diagnosis of sepsis developed swelling and hyperemia at the infusion site 10 days after an intraosseous infusion in the right proximal tibia. Physical examination showed a serous discharge from a fistula on the anteromedial side of the right proximal cruris. Plain radiographs demonstrated periosteal reaction in the right tibia and osteolytic areas in the proximal metaphysis. With a diagnosis of acute osteomyelitis, drainage and medullary irrigation were performed and parenteral antibiotic treatment was initiated. Cultures from the surgical site yielded Candida albicans, upon which fluconazole (8 mg/kg) treatment was administered for four weeks. A complete clinical and radiographic improvement was observed at the end of a 12-month follow-up.
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