Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Fluoride metabolism and fluorosis.

Deirdre Browne¹, Helen Whelton, Denis O'Mullane

¹Oral Health Services Research Centre, University Dental School, Wilton, Cork, Ireland. dm.browne@ucc.ie

Journal of Dentistry

|February 24, 2005

Summary

Enamel fluorosis risk increases with early tooth brushing and excessive fluoride. Delaying brushing until age 2 and using a pea-sized amount of fluoride toothpaste can mitigate this risk.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

'At a tipping point': a comparative analysis of oral health coverage for children across six European countries: Denmark, Germany, Hungary, Ireland, Scotland, and Spain.

BMC oral health·2025

Same author

'Rules of engagement': Does competition drive engagement in faculty development.

The clinical teacher·2024

Same author

Comparing oral health systems for children in six European countries to identify lessons learned for universal oral health coverage: A study protocol.

HRB open research·2023

Same author

A competitive edge: Developing a simulation faculty using competition.

The clinical teacher·2023

Same author

Development and validation of an International Patient's Attitudes to Prevention in Oral Health Questionnaire.

Community dentistry and oral epidemiology·2022

Same author

Exploring 12-Year trends in childhood obesity prevalence for the Republic of Ireland - a national study using survey data from 2002 and 2014.

HRB open research·2022

Area of Science:

Dental Public Health
Pediatric Dentistry
Fluoride Toxicology

Background:

Enamel fluorosis is the primary known risk of water fluoridation.
The prevalence of enamel fluorosis is rising globally.
Specific critical developmental periods exist for enamel fluorosis risk in children.

Purpose of the Study:

Review methods for measuring enamel fluorosis.
Investigate the causes and metabolism of enamel fluorosis.
Identify and manage risk factors for enamel fluorosis.

Main Methods:

Conducted a narrative review of published literature.
Focused on studies of fluoride ingestion during critical pre-eruptive enamel development periods.
Included analysis of fluoride toothpaste use, supplementation, and infant formula.

Main Results:

Early initiation of tooth brushing with fluoride toothpaste is a significant risk factor.
The quantity of fluoride toothpaste used is a key determinant of fluorosis incidence.
Age-specific risk periods for enamel fluorosis were identified.

Conclusions:

Commencing tooth brushing at age 2 is recommended.
Using a pea-sized amount (0.25g) of fluoride toothpaste is advised.
These measures can help reduce the incidence of dental fluorosis.

Related Experiment Videos