Related Experiment Video
Updated: Aug 19, 2026

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
Published on: January 13, 2017
Marine actinomycetes as a source of novel secondary metabolites
Hans-Peter Fiedler1, Christina Bruntner, Alan T Bull
1Mikrobiologisches Institut, Universität Tübingen, Auf der Morgenstelle 28, D-72076 Tübingen, Germany. hans-peter.fiedler@uni-tuebingen.de
Abstract:
A set of 600 actinomycetes strains which were isolated from marine sediments from various sites in the Pacific and Atlantic Oceans were screened for the production of bioactive secondary metabolites. Marine streptomycete strains were found to be producers of well known chemically diverse antibiotics isolated from terrestrial streptomycetes, as in the case of marine Micromonospora strains. New marine members of the rare genus Verrucosispora seem to be a promising source for novel bioactive secondary metabolites as shown in the case of the abyssomicin producing strain AB-18-032.
Related Concept Videos
Bacterial Phylum Actinobacteria
Production of Antibiotics
Bacterial Phylum Planctomycetes
Antifungal Agents
Fungal Phylum Ascomycota
Amino Acid Catabolism
