Environmental light and heredity are associated with adaptive changes in retinal DHA levels that affect retinal function
Related Experiment Video
Updated: Jul 30, 2026

A Novel Light Damage Paradigm for Use in Retinal Regeneration Studies in Adult Zebrafish
Published on: October 24, 2013
Robert E Anderson1, John S Penn
1Department of Cell Biology, University of Oklahoma Health Sciences Center, and Dean A. McGee Eye Institute, Oklahoma City, OK, USA. robert-anderson@ouhsc.edu
Abstract:
Retinas of rats and mice react to environmental and genetic stimuli by altering the level of DHA in their rod outer segment membranes. We propose that this adaptation is a neuroprotective response to control the number of photons captured by rhodopsin and the efficiency of visual transduction, under conditions where excessive activation of the transduction cascade could lead to cell death.
More Related Videos
09:10Direct-Coupled Electroretinogram (DC-ERG) for Recording the Light-Evoked Electrical Responses of the Mouse Retinal Pigment Epithelium
Published on: July 14, 2020
08:18Methodology for Studying Interactions of Vitamin A Membrane Receptors and Opsin Protein with their Ligands in Generating the Retinylidene Protein
Published on: October 4, 2024
Related Concept Videos
Genetic Lingo
Photoreceptors and Plant Responses to Light
Background and Environment Affect Phenotype
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
Photoreceptors and Visual Pathways
Human Genetics
The complex relationship between genetics and psychology is observable through common biological components such...
Gene-Environment Interactions