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An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
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[Recent advances for research on effect of estrogen on immune system]

Genhong Yao1, Yayi Hou

  • 1Medical School, Nanjing University, Nanjing 210093, China.

Wei Sheng Yan Jiu = Journal of Hygiene Research
|February 25, 2005
PubMed

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In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...