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Updated: Aug 19, 2026

A Procedure to Observe Context-induced Renewal of Pavlovian-conditioned Alcohol-seeking Behavior in Rats
Published on: September 19, 2014
Alcohol increases reliance on cues that signal acts of control
Cecile A Marczinski1, Mark T Fillmore
1Department of Psychology, University of Kentucky, Lexington, KY 40506-0044, USA.
Abstract:
This study examined the effects of alcohol on the ability to execute and inhibit behavior in a context in which preliminary information signaled the likelihood that a response should be executed or suppressed. Adults (N = 24) performed a cued go/no-go task that required quick responses to go targets and suppression of responses to no-go targets. Cue dependency was manipulated by varying the predictive validity of the cues, and performance was tested under 3 doses of alcohol: 0.00 g/kg, 0.45 g/kg, and 0.65 g/kg. Dose-dependent increases in cue dependence were only observed with highly predictive cues. Results suggest that alcohol-induced increases in stimulus control over behavior might be most likely in situations when stimulus control over behavior has already been established.
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