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Related Experiment Videos

Bilateral persistent hyperplastic primary vitreous.

D A Sanghvi1, C A Sanghvi, N C Purandare

  • 1Department of Radiology, Tata Memorial Hospital, Mumbai, India. darshanasanghvi1@hotmail.com

Australasian Radiology
|February 25, 2005
PubMed
Summary

Bilateral persistent hyperplastic primary vitreous (PHPV) is a rare condition causing leukokoria in infants. Ocular ultrasound can help diagnose this rare cause of bilateral leukokoria.

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Area of Science:

  • Ophthalmology
  • Pediatric Ophthalmology
  • Medical Imaging

Background:

  • Persistent hyperplastic primary vitreous (PHPV) is a congenital developmental anomaly of the eye.
  • It typically presents unilaterally and is sporadic, making bilateral cases exceptionally rare.

Observation:

  • A 5-month-old infant presented with bilateral leukokoria, prompting referral for ocular ultrasound.
  • Ultrasound revealed an echogenic band with blood flow in the left eye and an elevated echogenic mass in the right eye, both connected to the optic disc.

Findings:

  • The imaging findings were consistent with bilateral persistent hyperplastic primary vitreous (PHPV).
  • Bilateral PHPV is rare, accounting for only 2.4% of cases in one study.

Implications:

Related Experiment Videos

  • This case highlights the importance of considering bilateral PHPV in the differential diagnosis of bilateral leukokoria.
  • Ocular ultrasound is a valuable tool for diagnosing PHPV and differentiating it from other conditions like retinoblastoma.