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Updated: Apr 13, 2026

Development of Amelogenin-chitosan Hydrogel for In Vitro Enamel Regrowth with a Dense Interface
Published on: July 10, 2014
Materials chemistry: a synthetic enamel for rapid tooth repair
Kazue Yamagishi1, Kazuo Onuma, Takashi Suzuki
1FAP Dental Institute, 3-2-1, Kakinokizaka, 502 Meguro-ku, Tokyo 152-0022, Japan.
Abstract:
The conventional treatment of dental caries involves mechanical removal of the affected part and filling of the hole with a resin or metal alloy. But this method is not ideal for tiny early lesions because a disproportionate amount of healthy tooth must be removed to make the alloy or resin stick. Here we describe a dental paste of synthetic enamel that rapidly and seamlessly repairs early caries lesions by nanocrystalline growth, with minimal wastage of the natural enamel.

