Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Flavonolignans from Avena sativa.

Eva Wenzig1, Olaf Kunert, Daneel Ferreira

  • 1Department of Pharmacognosy, Institute of Pharmaceutical Sciences, Karl Franzens University of Graz, Universitätsplatz 4, A-8010 Graz, Austria.

Journal of Natural Products
|February 26, 2005
PubMed
Summary

Researchers discovered three novel flavonolignans in Avena sativa (oat) herb, marking the first identification of these compounds in this plant. The study details their unique chemical structures and configurations.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

International standards and good practice guidelines in traditional, complementary and integrative medicine: a scoping review.

Frontiers in pharmacology·2026
Same author

Bioactivities of <i>Alchemilla alpina</i> L. Extract on Women's Reproductive and Metabolic Health: Antioxidant, Enzyme Inhibitory, Receptor Modulatory Properties and Potential Cytotoxic Effects.

International journal of molecular sciences·2026
Same author

Paediatric Use of Herbal Medicinal Products: New Insights in RWD Generation - A Report on the RWD Workshop 2025 in Naples.

Planta medica·2026
Same author

Synthesis of some novel sulfonamides with coumarin core. An unexpected product of the reaction.

Acta chimica Slovenica·2026
Same author

Correction: Sesquiterpene lactones downregulate G2/M cell cycle regulator proteins and affect the invasive potential of human soft tissue sarcoma cells.

PloS one·2026
Same author

Structure Elucidation of Biflavones With Ether Bonds by NMR-Spectroscopy-Structure Revisions of Loniflavone and Methylloniflavone.

Magnetic resonance in chemistry : MRC·2025

Area of Science:

  • Phytochemistry
  • Natural Product Chemistry
  • Plant Biochemistry

Background:

  • Avena sativa (oat) is a widely cultivated cereal crop with a rich history in human nutrition.
  • Flavonolignans are a class of natural compounds with potential biological activities, but their presence in oats has not been previously documented.
  • Tricin is a known flavone found in oats, serving as a precursor for potential flavonolignan biosynthesis.

Purpose of the Study:

  • To isolate and characterize novel flavonolignans from Avena sativa herb.
  • To investigate the structural diversity of compounds derived from tricin in oats.
  • To report the first instance of flavonolignan discovery in Avena sativa.

Main Methods:

  • Extraction and isolation of compounds from Avena sativa herb.

Related Experiment Videos

  • Structure elucidation using 1D and 2D Nuclear Magnetic Resonance (NMR) spectroscopy.
  • Determination of absolute configuration via Circular Dichroism (CD) data analysis.

    • Main Results:

    • Three flavonolignans, derived from the flavone tricin, were successfully isolated from oat herb.
    • Two known compounds (1a, 1b) feature a coniferyl alcohol moiety linked via an ether bond to the flavone.
    • A new natural product (compound 2) exhibits a coniferyl alcohol moiety linked by C-C bonds, with its structure and absolute configuration elucidated.

    Conclusions:

    • This study represents the first report of flavonolignans in Avena sativa.
    • The identification of novel flavonolignans highlights the chemical richness of oat herb.
    • The distinct linkage in compound 2 provides new insights into flavonolignan biosynthesis and structural variation.