Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Gene duplications specific to the amphioxus lineage].

Wei Wang1, Bing Su, Yi-Quan Wang

  • 1College of Life Science, Xiamen University, Xiamen, 361005, China. wangwei_sz@eyou.com

Yi Chuan = Hereditas
|February 26, 2005
PubMed
Summary

Evolutionary developmental biology (Evo-Devo) uses amphioxus, a close vertebrate relative, to study vertebrate origins. Amphioxus genome evolution reveals independent gene duplications, not a direct ancestor, but a key relative.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Jasmonic Acid Biosynthesis and the Activation of Signal Transduction Pathway Play a Crucial Role in Alfalfa Adaptation to Drought Stress.

Journal of agricultural and food chemistry·2026
Same author

Lamprey 3D single-cell transcriptomics reveals ancestral and specialized features of the vertebrate brain.

Science (New York, N.Y.)·2026
Same author

In-depth serum proteomics atlas of COVID-19 defines a Severity-Resistance Index from a four-protein panel for disease severity and prognosis.

Journal of translational medicine·2026
Same author

m<sup>6</sup>A RNA modification guides alternative polyadenylation to maintain T cell quiescence.

Science advances·2026
Same author

Evolutionary specializations in primate cortical development.

Current opinion in genetics & development·2026
Same author

Viral-host interactions mediated by the mTOR signaling pathway.

Cell insight·2026

Area of Science:

  • Evolutionary developmental biology
  • Genomics
  • Comparative biology

Context:

  • Evolutionary developmental biology (Evo-Devo) integrates developmental and evolutionary biology to understand organismal complexity.
  • Cephalochordate amphioxus, the closest living relative to vertebrates, offers insights due to its conserved morphology and pre-duplicated genome.
  • Studying amphioxus aids in understanding vertebrate origins and morphological evolution.

Purpose:

  • To explore the evolutionary history of genes within the amphioxus lineage.
  • To analyze independent gene duplications in amphioxus and their implications for vertebrate evolution.
  • To clarify the phylogenetic position of amphioxus relative to vertebrates.

Summary:

  • Amphioxus, while morphologically conserved, exhibits independent gene duplications (e.g., Hox, Evx, HNF-3, Calmodulin-like) within its lineage.

Related Experiment Videos

  • These genomic particularities indicate amphioxus is not a direct vertebrate ancestor but a related species with unique evolutionary features.
  • The study highlights the dynamic nature of even conserved genomes and the importance of considering lineage-specific adaptations.

    • Impact:

    • Provides a nuanced understanding of vertebrate evolutionary history by examining a key relative.
    • Highlights the role of gene duplication in shaping genomes and driving morphological evolution.
    • Refines the interpretation of amphioxus as a model organism for studying vertebrate origins.