Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

PLATCOM: a Platform for Computational Comparative Genomics.

Kwangmin Choi1, Yu Ma, Jeong-Heyon Choi

  • 1School of Informatics, Indiana University, Bloomington, IN 47404, USA.

Bioinformatics (Oxford, England)
|February 26, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Validation of a 2-Gene Blood Test for Kawasaki Disease in Febrile Children.

JAMA network open·2026
Same author

Deep learning for predicting patient drug response by transferring gene-level and cell-level knowledge to tumors.

NPJ precision oncology·2026
Same author

Decreased PP2A expression and activity represent a therapeutic target for plexiform neurofibroma.

Acta neuropathologica communications·2026
Same author

Effects of Maternal Tetramethyl Bisphenol F Exposure on Neurodevelopment and Behavior in Mouse Offspring.

International journal of molecular sciences·2026
Same author

Enacted practices and developmental experiences of senior medical student tutors in a structured peer tutoring program.

Korean journal of medical education·2026
Same author

EnsDTI: Predicting Drug-Target Interaction With Mixture-of-Experts and Confidence Assessment.

IEEE transactions on computational biology and bioinformatics·2026
Same journal

conMItion: an R package adjusting confounding factors for associations in multi-omics.

Bioinformatics (Oxford, England)·2026
Same journal

SpaMFG: a Spatial Multi-omics Integration Method based on Feature Grouping.

Bioinformatics (Oxford, England)·2026
Same journal

CSCN: Inference of Cell-Specific Causal Networks Using Single-Cell RNA-Seq Data.

Bioinformatics (Oxford, England)·2026
Same journal

Sparse CCA-Based Mediation Analysis with High-Dimensional Exposures and Mediators.

Bioinformatics (Oxford, England)·2026
Same journal

Enhancing Cross-Context Generalization in Drug Perturbation Prediction with a Multimodal Conditional Diffusion Framework.

Bioinformatics (Oxford, England)·2026
Same journal

Primer Design through Submodular Function Estimation.

Bioinformatics (Oxford, England)·2026
See all related articles

This study introduces PLATCOM, a system for comparative genomics. It enables researchers to freely select genomes for analysis, overcoming limitations in current bioinformatics tools.

Area of Science:

  • Bioinformatics
  • Computational Biology
  • Genomics

Background:

  • Increasing availability of whole genome sequences necessitates advanced comparative analysis.
  • Challenges in comparative genomics include high computational demands and subjective genome selection.
  • A need exists for flexible bioinformatics systems for multi-genome comparison.

Purpose of the Study:

  • To present PLATCOM, an integrated system for comparative genomics.
  • To provide researchers with a platform for freely selecting and analyzing multiple genomes.

Main Methods:

  • PLATCOM integrates public databases and genome analysis applications.
  • The system facilitates data mining over internal databases.
  • Users can select specific genomes for comparative analysis.

Related Experiment Videos

Main Results:

  • PLATCOM enables visual investigation of genomic sequence similarities.
  • The system identifies conserved gene neighborhoods and metabolic pathways.
  • Putative gene fusion events can be detected across selected genomes.

Conclusions:

  • PLATCOM offers a user-friendly solution for comparative genomics.
  • The platform supports diverse biological discovery through multi-genome analysis.
  • Accessible at http://platcom.informatics.indiana.edu/platcom.