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Thyroid function in haemochromatosis
1Department of Endocrinology, South Infirmary, Victoria Hospital, Old Blackrock Road, Cork, Ireland.
Background:
In hereditary haemochromatosis (HH), the thyroid gland is the site of substantial iron deposition. However, there have been relatively few reported cases of thyroid dysfunction in HH.
Aim:
To evaluate the prevalence of thyroid disorders in a large group of patients with HH.
Methods:
A variety of endocrine investigations were undertaken including thyroid function tests and thyroid antibody studies.
Results:
A total of 154 consecutive patients (123 male, 31 female) were studied. One case of primary hypothyroidism was identified, giving a prevalence of 0.6%. Subclinical hypothyroidism was identified in two females, giving a prevalence of 1.3%. Iatrogenic hypothyroidism was identified in two other cases. No case of hyperthyroidism was identified.
Conclusion:
Thyroid dysfunction is an uncommon occurrence in patients with HH.
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