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Complications of the cardiopulmonary stress test in patients with depressed left ventricular systolic function
Ana T Timóteo1, Miguel Mendes, Carlos T Aguiar
1Serviço de Cardiologia, Hospital de Santa Cruz, Camaxide, Portugal. ana_timoteo@yahoo.com
Insights
Cardiopulmonary stress tests (CPX) carry a low complication risk (around 4%) in chronic heart failure patients, though higher than in those with normal function. These tests should be medically supervised in a hospital setting.
Area of Science:
- Cardiology
- Exercise Physiology
Background:
- Exercise testing generally has low complication risks.
- Theoretical concerns suggest higher risks for chronic heart failure (CHF) patients.
Purpose of the Study:
- To assess complications during cardiopulmonary stress tests (CPX) in patients with reduced left ventricular systolic function.
- Compare CPX complication rates between patients with depressed and normal left ventricular function.
Main Methods:
- Retrospective analysis of 334 CPX in patients with ejection fraction <40% (Group A) and 180 CPX in individuals with normal function (Group B).
- Comparison of demographic data, CPX parameters, and specific complications between groups.
Main Results:
- Major complications occurred in 4.2% of Group A patients (p = 0.012).
- Non-sustained ventricular tachycardia was more frequent in Group A.
- Absence of coronary artery disease independently predicted complications.
Conclusions:
- Major CPX complications were confined to patients with impaired left ventricular systolic function.
- CPX in heart failure patients presents a low but significantly higher complication risk than in normal function groups.
- CPX for heart failure patients is recommended in a hospital setting with physician supervision.
Background:
The exercise test has a recognized lower risk of complications when used in the general population and in coronary artery diseased patients, but from a theoretical point of view should have a higher rate of complications when performed in patients with chronic heart failure (CHF).
Aims:
To characterize and assess the type and incidence of complications during cardiopulmonary stress test (CPX) in patients with depressed left ventricular systolic function in comparison with a group of patients and individuals with normal function.
Methods:
Retrospective analysis of the 334 consecutive CPX performed for risk stratification in 198 patients with a left ventricular ejection fraction below 40% (Group A) and 180 consecutive CPX performed in 78 subjects with normal function (Group B). The two groups were compared with respect to demographic data, CPX parameters and specific complications.
Results:
Major complications during the tests occurred only in 14 tests of Group A (4.2%, p = 0.012). Non-sustained ventricular tachycardia, <6 beats, occurred in 7 group A and 2 group B tests. The absence of coronary artery disease was the only independent predictor for complications.
Conclusions:
Major CPX complications occurred only in patients with impaired left ventricular systolic function. Heart failure patients showed a low probability (around 4%) for complications during CPX, significantly higher and more severe than the risk in the group of patients with normal ventricular function, allowing us to recommend that CPX in patients with heart failure should be performed in a hospital setting under the supervision of a physician with specific training.
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